US route endpoint in
Pee Dee, SC

The south beginning of US 217 was to the left, more or less where US 301 splits off today (although these roads were not four-laned at the time, and there was no grade separation).  US 217 was decommissioned in 1932, when US 301 was extended along its entire corridor.  So then for about two years, the south beginning of US 301 was to the left, but it was not long before US 301 was extended further south from Pee Dee.